Michael Yarus - Professor
Ph.D., California Institute of Technology, 1965
RNA structure and function; RNA catalysis; mechanisms of translation; origins of translation.
This laboratory has engaged in three major types of scientific work:
- 1. on the fundamental reactions of the translational apparatus, and the roles of particular tRNA and mRNA sequences in translational efficiency and accuracy.
- 2. on the selection of particular RNA structures with binding or catalytic activity, and the relation of those activities to the origin of the genetic code, or translation in a larger sense.
- 3. on the nature of RNA affinity for phospholipid bilayers and on the role of such membrane RNAs in biology.
MCDB
(303) 492-8376 (lab) 492-7108/8377
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Porter B236
Legiewicz M, Lozupone C, Knight R, Yarus M, "Size, constant sequences, and optimal selection." RNA (New York, N.Y.) 11 (2005): 1701-9
Widmann J, Di Giulio M, Yarus M, Knight R, "tRNA creation by hairpin duplication." Journal of molecular evolution 61 (2005): 524-30
Janas T, Janas T, Yarus M, "A membrane transporter for tryptophan composed of RNA." RNA (New York, N.Y.) 10 (2004): 1541-9
Lozupone C, Changayil S, Majerfeld I, Yarus M, "Selection of the simplest RNA that binds isoleucine." RNA (New York, N.Y.) 9 (2003): 1315-22
Jadhav VR, Yarus M, "Acyl-CoAs from coenzyme ribozymes." Biochemistry 41 (2002): 723-9
Click here for the complete list of publications
Widmann J, Di Giulio M, Yarus M, Knight R, "tRNA creation by hairpin duplication." Journal of molecular evolution 61 (2005): 524-30
Janas T, Janas T, Yarus M, "A membrane transporter for tryptophan composed of RNA." RNA (New York, N.Y.) 10 (2004): 1541-9
Lozupone C, Changayil S, Majerfeld I, Yarus M, "Selection of the simplest RNA that binds isoleucine." RNA (New York, N.Y.) 9 (2003): 1315-22
Jadhav VR, Yarus M, "Acyl-CoAs from coenzyme ribozymes." Biochemistry 41 (2002): 723-9
