Greg Odorizzi - Associate Professor
Ph.D., University of California, San Diego, 1996
Genetics and cell biology; membrane trafficking and phosphoinositide signaling in eukaryotic cells.
The research in our lab involves a combination of genetics, biochemistry, fluorescence microscopy, electron microscopy, and electron tomography to investigate the molecular mechanisms of membrane trafficking in the endocytic pathway.
Our model system is the budding yeast Saccharomyces cerevisiae. The mechanisms that control membrane trafficking in yeast are highly conserved and function in humans as well as all other eukaryotic organisms.
MCDB
(303) 735-0179 (lab) 735-6518
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MCDB A420C
Richter C, West M, Odorizzi G, "Dual mechanisms specify Doa4-mediated deubiquitination at multivesicular bodies." The EMBO journal 26 (2007): 2454-64
McNatt MW, McKittrick I, West M, Odorizzi G, "Direct binding to Rsp5 mediates ubiquitin-independent sorting of Sna3 via the multivesicular body pathway." Molecular biology of the cell 18 (2007): 697-706
Nickerson DP, West M, Odorizzi G, "Did2 coordinates Vps4-mediated dissociation of ESCRT-III from endosomes." The Journal of cell biology 175 (2006): 715-20
Russell MR, Nickerson DP, Odorizzi G, "Molecular mechanisms of late endosome morphology, identity and sorting." Current opinion in cell biology 18 (2006): 422-8
Kim J, Sitaraman S, Hierro A, Beach BM, Odorizzi G, Hurley JH, "Structural basis for endosomal targeting by the Bro1 domain." Developmental cell 8 (2005): 937-47
Click here for the complete list of publications
McNatt MW, McKittrick I, West M, Odorizzi G, "Direct binding to Rsp5 mediates ubiquitin-independent sorting of Sna3 via the multivesicular body pathway." Molecular biology of the cell 18 (2007): 697-706
Nickerson DP, West M, Odorizzi G, "Did2 coordinates Vps4-mediated dissociation of ESCRT-III from endosomes." The Journal of cell biology 175 (2006): 715-20
Russell MR, Nickerson DP, Odorizzi G, "Molecular mechanisms of late endosome morphology, identity and sorting." Current opinion in cell biology 18 (2006): 422-8
Kim J, Sitaraman S, Hierro A, Beach BM, Odorizzi G, Hurley JH, "Structural basis for endosomal targeting by the Bro1 domain." Developmental cell 8 (2005): 937-47
