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On malleability in the genetic code
On malleability in the genetic code.
47
To explain now-numerous cases of codon reassignment (departure from the universal code), we suggest a pathway in which the transformed codon is temporarily ambiguous. All the unusual tRNA activities required have been demonstrated. In addition, the repetitive use of certain reassignments, the phylogenetic distribution of reassignments, and the properties of present-day reassinged tRNAs are each consistent with evolution of the code via an ambiguous translational intermediate.
Schultz DW, Yarus M
Journal of molecular evolution
1996-05-01 00:00
42
5
597-601
Codon,Evolution, Molecular,Genetic Code,Models, Genetic,Protein Biosynthesis,RNA, Transfer,Codon,RNA, Transfer
J. Mol. Evol.
0022-2844
1437
True
8662012
