Wang X, Wang J, Gengyo-Ando K, Gu L, Sun CL, Yang C, Shi Y, Kobayashi T, Shi Y, Mitani S, Xie XS, Xue D, "C. elegans mitochondrial factor WAH-1 promotes phosphatidylserine externalization in apoptotic cells through phospholipid scramblase SCRM-1." Nature cell biology 9 (2007): 541-9
Chang YS, Adnane J, Trail PA, Levy J, Henderson A, Xue D, Bortolon E, Ichetovkin M, Chen C, McNabola A, Wilkie D, Carter CA, Taylor IC, Lynch M, Wilhelm S, "Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models." Cancer chemotherapy and pharmacology 59 (2007): 561-74
Xue D, Elliott CM, Gong P, Grainger DW, Bignozzi CA, Caramori S, "Indirect electrochemical sensing of DNA hybridization based on the catalytic oxidation of cobalt (II)." Journal of the American Chemical Society 129 (2007): 1854-5
Kokel D, Xue D, "A class of benzenoid chemicals suppresses apoptosis in C. elegans." Chembiochem : a European journal of chemical biology 7 (2006): 2010-5
Kokel D, Li Y, Qin J, Xue D, "The nongenotoxic carcinogens naphthalene and para-dichlorobenzene suppress apoptosis in Caenorhabditis elegans." Nature chemical biology 2 (2006): 338-45
Yang C, Yan N, Parish J, Wang X, Shi Y, Xue D, "RNA aptamers targeting the cell death inhibitor CED-9 induce cell killing in Caenorhabditis elegans." The Journal of biological chemistry 281 (2006): 9137-44
Parrish JZ, Xue D, "Cuts can kill: the roles of apoptotic nucleases in cell death and animal development." Chromosoma 115 (2006): 89-97
Fadeel B, Xue D, "PS externalization: from corpse clearance to drug delivery." Cell death and differentiation 13 (2006): 360-2
Yan N, Chai J, Lee ES, Gu L, Liu Q, He J, Wu JW, Kokel D, Li H, Hao Q, Xue D, Shi Y, "Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans." Nature 437 (2005): 831-7
Breckenridge DG, Xue D, "Regulation of mitochondrial membrane permeabilization by BCL-2 family proteins and caspases." Current opinion in cell biology 16 (2004): 647-52
Yan N, Gu L, Kokel D, Chai J, Li W, Han A, Chen L, Xue D, Shi Y, "Structural, biochemical, and functional analyses of CED-9 recognition by the proapoptotic proteins EGL-1 and CED-4." Molecular cell 15 (2004): 999-1006
Kim SY, Valencia M, Lee ES, Park D, Oh M, Xue D, Park WJ, "Identification of CED-3 substrates by a yeast-based screening method." Molecular biotechnology 27 (2004): 1-6
Friedman J, Xue D, "To live or die by the sword: the regulation of apoptosis by the proteasome." Developmental cell 6 (2004): 460-1
Wang X, Wu YC, Fadok VA, Lee MC, Gengyo-Ando K, Cheng LC, Ledwich D, Hsu PK, Chen JY, Chou BK, Henson P, Mitani S, Xue D, "Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12." Science (New York, N.Y.) 302 (2003): 1563-6
Yang W, Guastella J, Huang JC, Wang Y, Zhang L, Xue D, Tran M, Woodward R, Kasibhatla S, Tseng B, Drewe J, Cai SX, "MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activity." British journal of pharmacology 140 (2003): 402-12
Parrish JZ, Yang C, Shen B, Xue D, "CRN-1, a Caenorhabditis elegans FEN-1 homologue, cooperates with CPS-6/EndoG to promote apoptotic DNA degradation." The EMBO journal 22 (2003): 3451-60
Parrish JZ, Xue D, "Functional genomic analysis of apoptotic DNA degradation in C. elegans." Molecular cell 11 (2003): 987-96
Wang X, Yang C, Chai J, Shi Y, Xue D, "Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans." Science (New York, N.Y.) 298 (2002): 1587-92
Parrish J, Li L, Klotz K, Ledwich D, Wang X, Xue D, "Mitochondrial endonuclease G is important for apoptosis in C. elegans." Nature 412 (2001): 90-4
Fadok VA, Xue D, Henson P, "If phosphatidylserine is the death knell, a new phosphatidylserine-specific receptor is the bellringer." Cell death and differentiation 8 (2001): 582-7
Parrish J, Metters H, Chen L, Xue D, "Demonstration of the in vivo interaction of key cell death regulators by structure-based design of second-site suppressors." Proceedings of the National Academy of Sciences of the United States of America 97 (2000): 11916-21
Barkett M, Xue D, Horvitz HR, Gilmore TD, "Phosphorylation of IkappaB-alpha inhibits its cleavage by caspase CPP32 in vitro." The Journal of biological chemistry 272 (1997): 29419-22
Xue D, Horvitz HR, "Caenorhabditis elegans CED-9 protein is a bifunctional cell-death inhibitor." Nature 390 (1997): 305-8
Xue D, Shaham S, Horvitz HR, "The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease." Genes & development 10 (1996): 1073-83
Xue D, Horvitz HR, "Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein." Nature 377 (1995): 248-51
Buchan AM, Gertler SZ, Huang ZG, Li H, Chaundy KE, Xue D, "Failure to prevent selective CA1 neuronal death and reduce cortical infarction following cerebral ischemia with inhibition of nitric oxide synthase." Neuroscience 61 (1994): 1-11
MacManus JP, Hill IE, Huang ZG, Rasquinha I, Xue D, Buchan AM, "DNA damage consistent with apoptosis in transient focal ischaemic neocortex." Neuroreport 5 (1994): 493-6
Xue D, Tu Y, Chalfie M, "Cooperative interactions between the Caenorhabditis elegans homeoproteins UNC-86 and MEC-3." Science (New York, N.Y.) 261 (1993): 1324-8
Xue D, Finney M, Ruvkun G, Chalfie M, "Regulation of the mec-3 gene by the C.elegans homeoproteins UNC-86 and MEC-3." The EMBO journal 11 (1992): 4969-79
Chang YS, Adnane J, Trail PA, Levy J, Henderson A, Xue D, Bortolon E, Ichetovkin M, Chen C, McNabola A, Wilkie D, Carter CA, Taylor IC, Lynch M, Wilhelm S, "Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models." Cancer chemotherapy and pharmacology 59 (2007): 561-74
Xue D, Elliott CM, Gong P, Grainger DW, Bignozzi CA, Caramori S, "Indirect electrochemical sensing of DNA hybridization based on the catalytic oxidation of cobalt (II)." Journal of the American Chemical Society 129 (2007): 1854-5
Kokel D, Xue D, "A class of benzenoid chemicals suppresses apoptosis in C. elegans." Chembiochem : a European journal of chemical biology 7 (2006): 2010-5
Kokel D, Li Y, Qin J, Xue D, "The nongenotoxic carcinogens naphthalene and para-dichlorobenzene suppress apoptosis in Caenorhabditis elegans." Nature chemical biology 2 (2006): 338-45
Yang C, Yan N, Parish J, Wang X, Shi Y, Xue D, "RNA aptamers targeting the cell death inhibitor CED-9 induce cell killing in Caenorhabditis elegans." The Journal of biological chemistry 281 (2006): 9137-44
Parrish JZ, Xue D, "Cuts can kill: the roles of apoptotic nucleases in cell death and animal development." Chromosoma 115 (2006): 89-97
Fadeel B, Xue D, "PS externalization: from corpse clearance to drug delivery." Cell death and differentiation 13 (2006): 360-2
Yan N, Chai J, Lee ES, Gu L, Liu Q, He J, Wu JW, Kokel D, Li H, Hao Q, Xue D, Shi Y, "Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans." Nature 437 (2005): 831-7
Breckenridge DG, Xue D, "Regulation of mitochondrial membrane permeabilization by BCL-2 family proteins and caspases." Current opinion in cell biology 16 (2004): 647-52
Yan N, Gu L, Kokel D, Chai J, Li W, Han A, Chen L, Xue D, Shi Y, "Structural, biochemical, and functional analyses of CED-9 recognition by the proapoptotic proteins EGL-1 and CED-4." Molecular cell 15 (2004): 999-1006
Kim SY, Valencia M, Lee ES, Park D, Oh M, Xue D, Park WJ, "Identification of CED-3 substrates by a yeast-based screening method." Molecular biotechnology 27 (2004): 1-6
Friedman J, Xue D, "To live or die by the sword: the regulation of apoptosis by the proteasome." Developmental cell 6 (2004): 460-1
Wang X, Wu YC, Fadok VA, Lee MC, Gengyo-Ando K, Cheng LC, Ledwich D, Hsu PK, Chen JY, Chou BK, Henson P, Mitani S, Xue D, "Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12." Science (New York, N.Y.) 302 (2003): 1563-6
Yang W, Guastella J, Huang JC, Wang Y, Zhang L, Xue D, Tran M, Woodward R, Kasibhatla S, Tseng B, Drewe J, Cai SX, "MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activity." British journal of pharmacology 140 (2003): 402-12
Parrish JZ, Yang C, Shen B, Xue D, "CRN-1, a Caenorhabditis elegans FEN-1 homologue, cooperates with CPS-6/EndoG to promote apoptotic DNA degradation." The EMBO journal 22 (2003): 3451-60
Parrish JZ, Xue D, "Functional genomic analysis of apoptotic DNA degradation in C. elegans." Molecular cell 11 (2003): 987-96
Wang X, Yang C, Chai J, Shi Y, Xue D, "Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans." Science (New York, N.Y.) 298 (2002): 1587-92
Parrish J, Li L, Klotz K, Ledwich D, Wang X, Xue D, "Mitochondrial endonuclease G is important for apoptosis in C. elegans." Nature 412 (2001): 90-4
Fadok VA, Xue D, Henson P, "If phosphatidylserine is the death knell, a new phosphatidylserine-specific receptor is the bellringer." Cell death and differentiation 8 (2001): 582-7
Parrish J, Metters H, Chen L, Xue D, "Demonstration of the in vivo interaction of key cell death regulators by structure-based design of second-site suppressors." Proceedings of the National Academy of Sciences of the United States of America 97 (2000): 11916-21
Barkett M, Xue D, Horvitz HR, Gilmore TD, "Phosphorylation of IkappaB-alpha inhibits its cleavage by caspase CPP32 in vitro." The Journal of biological chemistry 272 (1997): 29419-22
Xue D, Horvitz HR, "Caenorhabditis elegans CED-9 protein is a bifunctional cell-death inhibitor." Nature 390 (1997): 305-8
Xue D, Shaham S, Horvitz HR, "The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease." Genes & development 10 (1996): 1073-83
Xue D, Horvitz HR, "Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein." Nature 377 (1995): 248-51
Buchan AM, Gertler SZ, Huang ZG, Li H, Chaundy KE, Xue D, "Failure to prevent selective CA1 neuronal death and reduce cortical infarction following cerebral ischemia with inhibition of nitric oxide synthase." Neuroscience 61 (1994): 1-11
MacManus JP, Hill IE, Huang ZG, Rasquinha I, Xue D, Buchan AM, "DNA damage consistent with apoptosis in transient focal ischaemic neocortex." Neuroreport 5 (1994): 493-6
Xue D, Tu Y, Chalfie M, "Cooperative interactions between the Caenorhabditis elegans homeoproteins UNC-86 and MEC-3." Science (New York, N.Y.) 261 (1993): 1324-8
Xue D, Finney M, Ruvkun G, Chalfie M, "Regulation of the mec-3 gene by the C.elegans homeoproteins UNC-86 and MEC-3." The EMBO journal 11 (1992): 4969-79
