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Keeping the centrosome cycle on track Genome stability
Keeping the centrosome cycle on track. Genome stability.
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The protein kinase Mps1 and p53 both function in centrosome duplication and the spindle cell-cycle checkpoint. Defects in these functions can be potent sources of genomic instability by allowing mitosis to proceed with aberrant mitotic spindles.
Winey M
Current biology : CB
1996-08-01 00:00
6
8
962-4
Animals,Centrosome,Genome, Fungal,Protein-Serine-Threonine Kinases,Protein-Tyrosine Kinases,Saccharomyces cerevisiae,Saccharomyces cerevisiae Proteins,Tumor Suppressor Protein p53,Saccharomyces cerevisiae Proteins,Tumor Suppressor Protein p53,MPS1 protein, S cerevisiae,Protein-Tyrosine Kinases,Protein-Serine-Threonine Kinases
Department of Molecular, Cellular and Developmental Biology, University of Colorado at Boulder, Campus Box 347, Boulder, 80309-0347, USA
Curr. Biol.
0960-9822
1255
True
8805324
