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Identification of a third nuclear protei ... ene is Saccharomyces cerevisiae
Identification of a third nuclear protein-coding gene required specifically for posttranscriptional expression of the mitochondrial COX3 gene is Saccharomyces cerevisiae.
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A third nuclear protein-coding gene termed PET122 has been shown to be required for a post-transcriptional step in expression of the mitochondrial COX3 gene is Saccharomyces cerevisiae. pet122 mutants fail to produce cytochrome c oxidase subunit III, which is the polypeptide product of the COX3 gene, but produce normal amounts of mature COX3 mRNA. A strain bearing the pet122-1 allele is amber suppressible and correctly processes the 5' end of COX3 mRNA. Therefore, the PET122 gene product is a protein required for the expression of COX3 at some step after transcription and 5'-end processing of its transcript.
Kloeckener-Gruissem B, McEwen JE, Poyton RO
Journal of bacteriology
1988-03-01 00:00
170
3
1399-402
Electron Transport Complex IV,Fungal Proteins,Gene Expression Regulation,Genetic Complementation Test,Linkage (Genetics),Mitochondria,Nuclear Proteins,RNA Processing, Post-Transcriptional,Saccharomyces cerevisiae,Fungal Proteins,Nuclear Proteins,Electron Transport Complex IV
Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder 80309-0347
J. Bacteriol.
NIGMS GM29838, NIGMS GM30228
0021-9193
1038
True
2830240
