Document Actions
The AP-3 complex a coat of many colours
The AP-3 complex: a coat of many colours.
29
A new adaptor protein complex, termed AP-3, has recently been identified in mammalian cells, and genetic studies in yeast have revealed a functional role for the AP-3 complex in cargo-selective transport via a new alternative trafficking pathway from the Golgi to the vacuole/lysosome. Here, the authors review what is currently known about the AP-3 complex and discuss recent insight into its function in multicellular organisms that has come from the finding that mutations in AP-3 subunits correspond to classical mutations in Drosophila and mice.
Odorizzi G, Cowles CR, Emr SD
Trends in cell biology
1998-07-01 00:00
8
7
282-8
Adaptor Proteins, Vesicular Transport,Animals,Biological Transport,Enzyme Inhibitors,Eukaryotic Cells,Golgi Apparatus,Lysosomes,Monomeric Clathrin Assembly Proteins,Nerve Tissue Proteins,Phosphoproteins,Adaptor Proteins, Vesicular Transport,Enzyme Inhibitors,Monomeric Clathrin Assembly Proteins,Nerve Tissue Proteins,Phosphoproteins,clathrin assembly protein AP180
Division of Cellular and Molecular Medicine, University of California, San Diego, La Jolla 92093-0668, USA
Trends Cell Biol.
0962-8924
S0962-8924(98)01295-1
848
True
9714600
