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Archaeal introns splicing, intercellular mobility and evolution


Archaeal introns: splicing, intercellular mobility and evolution.

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Until recently, it appeared that archaeal introns were spliced by a process specific to the archaeal domain in which an endoribonuclease cuts a 'bulge-helix-bulge' motif that forms at exon-intron junctions. Recent results, however, have shown that the endoribonuclease involved in archaeal intron splicing is a homologue of two subunits of the enzyme complex that excises eukaryotic nuclear tRNA introns. Moreover, some archaeal introns encode homing enzymes that are also encoded by group I introns.


Lykke-Andersen J, Aagaard C, Semionenkov M, Garrett RA

Trends in biochemical sciences

1997-09-01 00:00

22

9

326-31

Archaea,Evolution, Molecular,Introns,Models, Molecular,Nucleic Acid Conformation,Phylogeny,RNA Splicing,RNA, Bacterial,RNA, Transfer,RNA, Bacterial,RNA, Transfer

RNA Regulation Centre, University of Copenhagen, Denmark

Trends Biochem. Sci.


0968-0004


S0968000497011134


802

True

9301331

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