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When Ras signaling reaches the mediator
When Ras signaling reaches the mediator.
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Numerous sequence-specific DNA binding proteins that couple extracellular stimuli to transcriptional regulation have been described. Less well understood is how these transcriptional regulators interact with the Mediator complex to initiate transcription and how those interactions are coordinated with the activation of signaling pathways. Recent work has begun to shed light on this important area of research.
Eastburn D, Han M
Developmental cell
2004-02-01 00:00
6
2
158-9
Animals,CCAAT-Enhancer-Binding Proteins,DNA-Binding Proteins,Gene Expression Regulation,Genes, ras,Models, Biological,Proto-Oncogene Proteins,Signal Transduction,Trans-Activation (Genetics),Transcription Factor CHOP,Transcription Factors,Transcription, Genetic,CCAAT-Enhancer-Binding Proteins,DNA-Binding Proteins,Proto-Oncogene Proteins,Transcription Factors,Transcription Factor CHOP
Howard Hughes Medical Institute, Department of Molecular, Cellular, and Developmental Biology, University of Colorado at Boulder, Boulder, CO 80309, USA
Dev. Cell
1534-5807
S1534580704000292
531
True
14960267
