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A cytogenetic analysis of the Punch-tudo ... e 2R in Drosophila melanogaster
A cytogenetic analysis of the Punch-tudor region of chromosome 2R in Drosophila melanogaster.
3
Eleven chromosomal deficiencies and several rearrangements in the Pu-tud region of chromosome 2R have been generated and examined cytologically. The Pu locus has been localized to chromosome bands 57C5-6 and tud to 57C7-8. Mutagenesis within the region defined by the deletion intervals has resulted in the isolation of 92 new lethal mutations. Seventy-six of these mutations have been separated into 16 complementation groups that have been ordered and placed cytologically by deletion mapping. All new alleles fully complement tud for both lethal and grandchildless phenotypes. The largest number of new mutations, a total of 25, are Pu alleles.
O'Donnell J, Boswell R, Reynolds T, Mackay W
Genetics
1989-02-01 00:00
121
2
273-80
Aminohydrolases,Animals,Chromosome Banding,Chromosome Deletion,Chromosome Mapping,Chromosomes,Drosophila melanogaster,Female,GTP Cyclohydrolase,Gene Rearrangement,Genes, Lethal,Male,Mutation,Aminohydrolases,GTP Cyclohydrolase
Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213
Genetics
NIGMS GM26757, NIGMS GM36937
0016-6731
86
True
2499509
