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Gene clusters and polycistronic transcription in eukaryotes


Gene clusters and polycistronic transcription in eukaryotes.

89

Sometimes genes are arranged nonrandomly on the chromosomes of eukaryotes. This review considers instances of gene clusters in which two genes or more are expressed from a single promoter. This includes cases in which a polycistronic pre-mRNA is processed to make monocistronic mRNAs in nematodes, as well as isolated examples of polycistronic mRNAs found in mammals, flies, and perhaps plants.


Blumenthal T

BioEssays : news and reviews in molecular, cellular and developmental biology

1998-06-01 00:00

20

6

480-7

Alternative Splicing,Animals,Base Sequence,Caenorhabditis elegans,Drosophila,Eukaryotic Cells,Evolution, Molecular,Genes,Multigene Family,Operon,Plants,RNA, Messenger,Transcription, Genetic,Trypanosoma,RNA, Messenger

Department of Biochemistry and Molecular Genetics, University of Colorado Health Sciences Center, Denver 80262, USA TomBlumenthaluchscedu

Bioessays

NIGMS GM42432

0265-9247

10.1002/(SICI)1521-1878(199806)20:6<480::AID-BIES6>3.0.CO;2-Q

10.1002/(SICI)1521-1878(199806)20:6<480::AID-BIES6>3.0.CO;2-Q

39

True

9699460

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