Brian DeDecker

Research Associate

Photo of Brian DeDecker

Brian.DeDecker@Colorado.EDU
Phone: (303) 492-2712
EXT: 2-2712
LAB: 2-2257

Office Location

GOLD A318

Education

Ph.D., Yale University, 1997

Selected Publications

Modifiers of notch transcriptional activity identified by genome-wide RNAi.
Mourikis, P, Lake, RJ, Firnhaber, CB, and DeDecker, BS BMC Dev Biol, 10:107. 2010

Noble metals strip peptides from class II MHC proteins.
De Wall, SL, Painter, C, Stone, JD, Bandaranayake, R, Wiley, DC, Mitchison, TJ, Stern, LJ, and DeDecker, BS Nat Chem Biol, 2(4):197-201. 2006

Structural distortion of p53 by the mutation R249S and its rescue by a designed peptide: implications for "mutant conformation".
Friedler, A, DeDecker, BS, Freund, SMV, Blair, C, Rudiger, S, and Fersht, AR J Mol Biol, 336(1):187-96. 2004

Allosteric drugs: thinking outside the active-site box.
DeDecker, BS Chem Biol, 7(5):R103-7. 2000

Hot-spot mutants of p53 core domain evince characteristic local structural changes.
Wong, KB, DeDecker, BS, Freund, SM, Proctor, MR, Bycroft, M, and Fersht, AR Proc Natl Acad Sci U S A, 96(15):8438-42. 1999

The crystal structure of a hyperthermophilic archaeal TATA-box binding protein.
DeDecker, BS, O'Brien, R, Fleming, PJ, Geiger, JH, Jackson, SP, and Sigler, PB J Mol Biol, 264(5):1072-84. 1996